Dlin-MC3-DMA: Mechanistic Advances in Lipid Nanoparticle ...

2025-09-22

Explore the molecular mechanisms and predictive modeling that underpin Dlin-MC3-DMA’s pivotal role as an ionizable cationic liposome in lipid nanoparticle siRNA delivery, mRNA drug delivery, and hepatic gene silencing. This article synthesizes emerging evidence and practical guidance for effective LNP formulation.

Dlin-MC3-DMA in Lipid Nanoparticle siRNA and mRNA Deliver...

2025-09-19

Dlin-MC3-DMA: Advances in Ionizable Cationic Liposomes fo...

2025-09-18

Dlin-MC3-DMA, an ionizable cationic liposome, is a pivotal component in lipid nanoparticle siRNA delivery and mRNA drug delivery lipid systems. This article examines its molecular advantages, delivery mechanisms, and recent machine learning-guided optimization strategies, offering new perspectives for hepatic gene silencing and cancer immunochemotherapy applications.